Source: Nobel Prize https://youtu.be/5AiFVch_fV8
The Nobel Assembly at Karolinska Institutet has awarded the
2016 Nobel Prize in Physiology or Medicine to Yoshinori Ohsumi for his contribution
in discovery of mechanisms for autophagy.
This year's Nobel Laureate discovered and elucidated
mechanisms underlying autophagy, a fundamental process for degrading and
recycling cellular components.
Key publications:
Takeshige K, Baba M, Tsuboi S, Noda T, Ohsumi Y. (1992). Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. Journal of Cell Biology. 1992;119: 301-311.
Tsukada M, Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cervisiae. FEBS Letters. 1993;333:169-174. DOI: 10.1016/0014-5793(93)80398-E
Mizushima N, Noda T, Yoshimori T, Tanaka Y, Ishii T, George MD, et al. (1998). A protein conjugation system essential for autophagy. Nature. 1998;395:395-398. DOI: 10.1038/26506
Ichimura Y, Kirisako T, Takao T, Satomi Y, Shimonishi Y, Ishihara N, et al. A ubiquitin-like system mediates protein lipidation. Nature, 2000;408:488-492. DOI: 10.1038/35044114
